01
Import
Load bounded CSV plate-reader data
Dose-response and relative-potency assay software
Provenarium for traceable assay analysis.
Provenarium takes plate-reader CSV data through plate and dilution mapping, supplier-tested restricted-4PL fitting, system-suitability evaluation, documented exclusions, and a deterministic PDF report.
CSV import Restricted 4PL model Exclusion reasons Settings retained with results PDF reports
ANALYSIS / EXAMPLE-04Relative potency · 4PL
restricted fitRelative potency80.0%within configured range
Slope ratio1.00criterion passed
DispositionPassedall configured checks
Dose–response fitReference Test
All configured suitability checks passed
Included with the resultSource data + analysis configuration fingerprints
AnalysisPlate import through PDF reportSource data and analysis configuration fingerprintsTeam workspaceInvitations, roles, member lifecycle, and organization-scoped analysis
One assay workflow
From raw measurements to a finished report.
Import the reader file, define the plate and dilution series, fit the response model, assess suitability, document exclusions, and generate the PDF without rebuilding the analysis in another tool.
02
Map
Assign samples, references, and replicates
03
Dilute
Calculate concentrations from the series
04
Fit
Run the restricted 4PL model
05
Evaluate
Apply configured suitability criteria
06
Inspect
Review curves, parameters, and exclusions
07
Report
Generate the complete formatted PDF
Why the workflow matters
A fitted curve does not show how the result was produced.
Potency teams often have to reconstruct which settings were used, how wells mapped to samples, why a value was excluded, and which report belongs with the source file. Provenarium includes those details in the completed analysis result and report.
Files and settings end up in different places
Reader files, plate maps, dilution calculations, and model settings are easy to separate when an analysis spans several tools.
Reviewers cannot see how the result was calculated
A curve and summary value do not explain the sample assignments, exclusions, suitability criteria, or model settings.
Report preparation adds manual steps
Analysts copy values and plots into another document instead of generating the PDF directly from the analysis results.
Controlled Team methods
Approve immutable method versions for locked routine runs.
A method version retains the complete run-independent recipe. Approval authorizes that exact version for routine use in Provenarium; it is not a claim that the method or customer workflow is validated, qualified, certified, or compliant.
01Draft
02In review
03Approved
04Routine run
05New version
06Retired
Immutable method versionAvailable in Team
Relative potency · 4PL
Version history3 revisionsMethod ownerBioassay teamStatusApproved for routine use
Canonical review historyReview assignments, decisions, reasons, actors, and times remain linked to the exact method version.
Analysis history and trending
Inspect, compare, review, and trend completed analyses.
Open retained analysis evidence, compare exactly two canonical records without recalculation, or filter compatible routine results by method, date, and metric. Trending presents one explainable rule-based signal; it does not make a release decision.
4PL / restricted fit
Fit the model and calculate potency
Each run records the plate map, model settings, exclusions, suitability criteria, results, and report settings.
Fit criterion Passed Slope ratio Passed Replicate CV Passed
Review suitability and exclusions
Check observed values, fitted parameters, suitability results, exclusion reasons, and the generated PDF.
Explainable signalAvailable now
Inspect routine performance
Filter compatible routine analyses by method version, date, and metric and inspect the retained points behind the displayed rule-based signal.
For regulated bioassay teams
Use supplier-tested controls and retained evidence within your quality system.
Provenarium's controlled routine workflow is not currently claimed to be 21 CFR Part 11 compliant. FDA does not certify software, and each customer must validate or qualify its configured workflow for intended use.
Completed analyses retain source and configuration identities, the producing platform release, scientific results, exclusions, suitability outcomes, and exact reports. Team adds controlled method versions, locked routine runs, electronic signatures for every new method approval, canonical history, comparison, and trending.
Review validation support and customer responsibilitiesINCLUDED WITH EACH ANALYSISRecords needed to review the result
Recorded software version Source data and analysis configuration fingerprints Required exclusion reasons Analyst, date, and run details
Validation is specific to your useYour organization defines intended use, approves procedures, trains users, and validates its configured workflow.
Ways to use Provenarium
Choose a free Personal workspace, an annual Team workspace, or custom development.
Team is manually onboarded for contracted named seats and billed annually by invoice. It adds controlled methods, locked routine runs, mandatory electronic signatures for new method approvals, canonical history, comparison, and trending. Customer-specific audit-trail adequacy conclusions, configurable retention, and customer release approval are not product capabilities. Custom work can be scoped separately.
Personal
Run a complete relative-potency analysis in your private personal workspace, free.
- Personal workspace
- CSV plate import
- Restricted 4PL fitting
- Retained analysis evidence and PDF export
Team
Manually onboard one organization workspace for a contracted number of named seats, billed annually by invoice.
- Organization workspace with owner, administrator, member, and reviewer roles
- Immutable method versions with draft, review, approved, and retired lifecycle states
- Exact-record electronic signatures for every new method approval
- Locked routine execution from an approved compatible method version
- Canonical method-review and access history
- Immutable completed analyses, directly downloadable PDF reports, and exact two-analysis comparison
- Method/date/metric trending with one explainable rule-based signal
Consulting + custom development
Add assay-specific calculations, file imports, reports, integrations, migration, or implementation support beyond the Team plan.
- Custom assay models and calculations
- Assay-specific import and analysis workflows
- Custom reports and data-exchange formats
- Plate-reader, LIMS, ELN, and other system integrations
- Customer-specific data migration, implementation, and support for customer validation
Personal workspace
Run the 4PL example from CSV through the finished PDF report.
Define the plate layout and dilution series, fit the curves, evaluate suitability, and inspect the final report—or tell us how your method differs.